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Dihydrolipoic acid

CAS No. 462-20-4

Dihydrolipoic acid( USAF XR-12 | Reduced lipoic acid | Reduced thioctic acid | 6,8-Dihydrothioctic acid | DHLA )

Catalog No. M27379 CAS No. 462-20-4

Dihydrolipoic acid, a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dihydrolipoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Dihydrolipoic acid, a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.
  • Description
    Dihydrolipoic acid, a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.
  • In Vitro
    ——
  • In Vivo
    Animal Model: Adult male Sprague-Dawley (SD) rats (weight, 200-220?g)Dosage:15?mg/kg, 30?mg/kg, 60?mg/kg Administration:Injected intraperitoneally daily Result:Treatment with 30?mg/kg and 60?mg/kg improved the body weight gain as compared to the LPS group.
  • Synonyms
    USAF XR-12 | Reduced lipoic acid | Reduced thioctic acid | 6,8-Dihydrothioctic acid | DHLA
  • Pathway
    Others
  • Target
    Antioxidant
  • Recptor
    Antioxidant
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    462-20-4
  • Formula Weight
    208.33
  • Molecular Formula
    C8H16O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (479.98 mM)
  • SMILES
    OC(=O)CCCCC(S)CCS
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang BD, Yang ZY, Li TR. Synthesis, characterization, and DNA-binding properties of the Ln(III) complexes with 6-hydroxy chromone-3-carbaldehyde-(2'-hydroxy) benzoyl hydrazone. Bioorg Med Chem. 2006 Sep 1;14(17):6012-21. doi: 10.1016/j.bmc.2006.05.015. Epub 2006 Jun 14. PMID: 16781158.
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