
Dihydrolipoic acid
CAS No. 462-20-4
Dihydrolipoic acid( USAF XR-12 | Reduced lipoic acid | Reduced thioctic acid | 6,8-Dihydrothioctic acid | DHLA )
Catalog No. M27379 CAS No. 462-20-4
Dihydrolipoic acid, a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.
Purity : >98% (HPLC)






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Biological Information
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Product NameDihydrolipoic acid
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NoteResearch use only, not for human use.
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Brief DescriptionDihydrolipoic acid, a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.
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DescriptionDihydrolipoic acid, a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.
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In Vitro——
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In VivoAnimal Model: Adult male Sprague-Dawley (SD) rats (weight, 200-220?g)Dosage:15?mg/kg, 30?mg/kg, 60?mg/kg Administration:Injected intraperitoneally daily Result:Treatment with 30?mg/kg and 60?mg/kg improved the body weight gain as compared to the LPS group.
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SynonymsUSAF XR-12 | Reduced lipoic acid | Reduced thioctic acid | 6,8-Dihydrothioctic acid | DHLA
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PathwayOthers
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TargetAntioxidant
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RecptorAntioxidant
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Research Area——
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Indication——
Chemical Information
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CAS Number462-20-4
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Formula Weight208.33
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Molecular FormulaC8H16O2S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (479.98 mM)
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SMILESOC(=O)CCCCC(S)CCS
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wang BD, Yang ZY, Li TR. Synthesis, characterization, and DNA-binding properties of the Ln(III) complexes with 6-hydroxy chromone-3-carbaldehyde-(2'-hydroxy) benzoyl hydrazone. Bioorg Med Chem. 2006 Sep 1;14(17):6012-21. doi: 10.1016/j.bmc.2006.05.015. Epub 2006 Jun 14. PMID: 16781158.
molnova catalog



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