Dihydrolipoic acid

CAS No. 462-20-4

Dihydrolipoic acid( USAF XR-12 | Reduced lipoic acid | Reduced thioctic acid | 6,8-Dihydrothioctic acid | DHLA )

Catalog No. M27379 CAS No. 462-20-4

Dihydrolipoic acid, a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 30 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Dihydrolipoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Dihydrolipoic acid, a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.
  • Description
    Dihydrolipoic acid, a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.
  • In Vitro
    ——
  • In Vivo
    Animal Model: Adult male Sprague-Dawley (SD) rats (weight, 200-220?g)Dosage:15?mg/kg, 30?mg/kg, 60?mg/kg Administration:Injected intraperitoneally daily Result:Treatment with 30?mg/kg and 60?mg/kg improved the body weight gain as compared to the LPS group.
  • Synonyms
    USAF XR-12 | Reduced lipoic acid | Reduced thioctic acid | 6,8-Dihydrothioctic acid | DHLA
  • Pathway
    Others
  • Target
    Antioxidant
  • Recptor
    Antioxidant
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    462-20-4
  • Formula Weight
    208.33
  • Molecular Formula
    C8H16O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (479.98 mM)
  • SMILES
    OC(=O)CCCCC(S)CCS
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang BD, Yang ZY, Li TR. Synthesis, characterization, and DNA-binding properties of the Ln(III) complexes with 6-hydroxy chromone-3-carbaldehyde-(2'-hydroxy) benzoyl hydrazone. Bioorg Med Chem. 2006 Sep 1;14(17):6012-21. doi: 10.1016/j.bmc.2006.05.015. Epub 2006 Jun 14. PMID: 16781158.
molnova catalog
related products
  • Riparin III

    Riparin III (Riparin) is a smooth muscle relaxant that inhibits CaCl2-induced contractions.Riparin III has potential antioxidant, anti-inflammatory, and antidepressant properties, and may reverse the most abnormal behavioral and neurochemical changes induced by corticosterone.

  • Sodium erythorbate

    Almost odorless fluffy, white to off-white crystalline powder. Used as an antioxidant and preservative.

  • DIM-C-pPhOH

    Nur77 (NR4A1) antagonist. Inhibits TGF-β induced cell migration of breast cancer cell lines. Promotes ROS/endoplasmic reticulum stress and proapoptotic pathways in pancreatic cancer cell lines.